Molecule Details
InChIKeyAQKQATGZIKRZMQ-UHFFFAOYSA-N
Compound Name4-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)-N-(3,4,5-trimethoxyphenyl)-1,3,5-triazin-2-amine
Canonical SMILESCOc1cc(Nc2ncnc(N3CCCc4cc(C)ccc43)n2)cc(OC)c1OC
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)16
Pfam Stratification Cross-Family
Avg pChEMBL6.08
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
P36507 MAP2K2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
O96013 PAK4 Homo sapiens Human PF00786 PF00069 6.2 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.2 Ki ChEMBL
P04629 NTRK1 Homo sapiens Human PF13855 PF16920 PF07714 PF18613 6.1 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.1 Ki ChEMBL
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.1 Ki ChEMBL
Q16620 NTRK2 Homo sapiens Human PF07679 PF13855 PF16920 PF01462 PF07714 6.1 Ki ChEMBL
Q7L7X3 TAOK1 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.1 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.0 Ki ChEMBL
P34947 GRK5 Homo sapiens Human PF00069 PF00615 6.0 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.0 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.0 Ki ChEMBL
P51955 NEK2 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q04759 PRKCQ Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.0 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.0 Ki ChEMBL