Molecule Details
InChIKeyAQDWLHMFJHACCX-UHFFFAOYSA-N
Compound Name1-[[2-chloro-5-(2-pyridin-4-ylethenyl)-3-pyridinyl]oxy]-3-(1H-indol-3-yl)propan-2-amine
Canonical SMILESNC(COc1cc(C=Cc2ccncc2)cnc1Cl)Cc1c[nH]c2ccccc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL6.83
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 8.0 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 7.3 Ki ChEMBL
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 7.2 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.9 Ki ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.6 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.4 Ki ChEMBL
P31751 AKT2 Homo sapiens Human PF00169 PF00069 PF00433 6.1 Ki ChEMBL
Q9Y243 AKT3 Homo sapiens Human PF00169 PF00069 PF00433 6.1 Ki ChEMBL