5-hydroxy-8-[4-[4-[3-[(E)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]oxybutyl]piperazin-1-yl]-4H-1,4-benzoxazin-3-one

InChIKey	`AQCPIJGBSDFUKW-CVKSISIWSA-N`
Compound Name	5-hydroxy-8-[4-[4-[3-[(E)-hydroxyiminomethyl]pyrazolo[1,5-a]pyridin-5-yl]oxybutyl]piperazin-1-yl]-4H-1,4-benzoxazin-3-one
Canonical SMILES	`O=C1COc2c(N3CCN(CCCCOc4ccn5ncc(/C=N/O)c5c4)CC3)ccc(O)c2N1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Homologous
Avg pChEMBL	8.3
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P35462	DRD3	Homo sapiens	Human	PF00001	9.5	Ki	ChEMBL;BindingDB
P14416	DRD2	Homo sapiens	Human	PF00001	9.0	Ki	ChEMBL;BindingDB
P21917	DRD4	Homo sapiens	Human	PF00001	8.6	Ki	ChEMBL;BindingDB
P28223	HTR2A	Homo sapiens	Human	PF00001	6.1	Ki	ChEMBL