Molecule Details
| InChIKey | APUFNRAMLCSAKF-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-Chloro-5-[(1h-Imidazo[4,5-C]quinolin-2-Ylsulfanyl)acetyl]benzenesulfonamide |
| Canonical SMILES | NS(=O)(=O)c1cc(C(=O)CSc2nc3cnc4ccccc4c3[nH]2)ccc1Cl |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.08 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 10.0 | Ki | ChEMBL |
| P00915 | CA1 | Homo sapiens | Human | PF00194 | 8.9 | Ki | ChEMBL |
| P00918 | CA2 | Homo sapiens | Human | PF00194 | 7.5 | Kd | ChEMBL;BindingDB |
| P43166 | CA7 | Homo sapiens | Human | PF00194 | 7.0 | Kd | ChEMBL;BindingDB |
| Q8N1Q1 | CA13 | Homo sapiens | Human | PF00194 | 7.0 | Kd | ChEMBL;BindingDB |