Molecule Details
| InChIKey | APPRVPLQWUIXSC-UHFFFAOYSA-N |
|---|---|
| Compound Name | hAChE-IN-5 |
| Canonical SMILES | Nc1n[nH]c2nc(-c3ccc(Br)cc3)cc(-c3ccc(Br)cc3)c12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.64 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P06276 | BCHE | Homo sapiens | Human | PF08674 PF00135 | 6.8 | IC50 | ChEMBL |
| P22303 | ACHE | Homo sapiens | Human | PF08674 PF00135 | 6.8 | IC50 | ChEMBL |
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 6.7 | IC50 | ChEMBL |
| P05067 | APP | Homo sapiens | Human | PF10515 PF12924 PF12925 PF02177 PF03494 PF00014 | 6.3 | IC50 | ChEMBL |