Molecule Details
| InChIKey | APHFSWUAUANWQN-UHFFFAOYSA-N |
|---|---|
| Compound Name | US10208024, Example 64 |
| Canonical SMILES | COCCN1CCC(n2cc(-c3cnc(N)c(-c4ccc(=O)n(-c5ccc6cc(C)cnc6c5)n4)n3)cn2)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.09 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P21802 | FGFR2 | Homo sapiens | Human | PF07679 PF13927 PF07714 | 7.4 | IC50 | ChEMBL;BindingDB |
| P11362 | FGFR1 | Homo sapiens | Human | PF07679 PF00047 PF07714 | 7.2 | IC50 | ChEMBL;BindingDB |
| P22607 | FGFR3 | Homo sapiens | Human | PF21165 PF07679 PF13927 PF07714 | 6.7 | IC50 | ChEMBL;BindingDB |