Molecule Details
| InChIKey | AOLMNCAPVYTEHC-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-Methyl-1-(4-methylpiperazin-1-yl)-2-[4-[2-(6-pyridin-4-ylimidazo[1,2-a]pyridin-2-yl)acetyl]phenyl]propan-1-one |
| Canonical SMILES | CN1CCN(C(=O)C(C)(C)c2ccc(C(=O)Cc3cn4cc(-c5ccncc5)ccc4n3)cc2)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.73 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9HAZ1 | CLK4 | Homo sapiens | Human | PF00069 | 7.3 | IC50 | ChEMBL |
| P49759 | CLK1 | Homo sapiens | Human | PF00069 | 6.9 | IC50 | ChEMBL |
| Q13627 | DYRK1A | Homo sapiens | Human | PF00069 | 6.9 | IC50 | ChEMBL |
| P49760 | CLK2 | Homo sapiens | Human | PF00069 | 6.8 | IC50 | ChEMBL |
| Q9Y463 | DYRK1B | Homo sapiens | Human | PF00069 | 6.3 | IC50 | ChEMBL |
| P49761 | CLK3 | Homo sapiens | Human | PF00069 | 6.1 | IC50 | ChEMBL |