Molecule Details
InChIKeyAOFJRBMLTUGMMP-UHFFFAOYSA-N
Compound Name4-cyano-N-(1-methyl-5-(N-methylcyclohexanecarboxamido)-1H-benzo[d]imidazol-2-yl)benzamide
Canonical SMILESCN(C(=O)C1CCCCC1)c1ccc2c(c1)nc(NC(=O)c1ccc(C#N)cc1)n2C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Cross-Family
Avg pChEMBL6.55
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 8.0 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.9 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.7 Ki ChEMBL
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 6.6 Ki ChEMBL
Q08881 ITK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 6.6 IC50 ChEMBL;BindingDB
Q96SB4 SRPK1 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.4 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.4 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 6.1 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.0 Ki ChEMBL