Molecule Details
InChIKeyAOBLBPWPSKBHSI-UHFFFAOYSA-N
Compound Name5-(1-benzyl-5-iodotriazol-4-yl)-1H-indazol-3-amine
Canonical SMILESNc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3I)cc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)55
Pfam Stratification Cross-Family
Avg pChEMBL6.81
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (55)
Target Gene Organism Category Pfam pChEMBL Type Source
P51817 PRKX Homo sapiens Human PF00069 8.3 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 8.0 Ki ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 7.9 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.9 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 7.8 Ki ChEMBL;BindingDB
O75582 RPS6KA5 Homo sapiens Human PF00069 PF00433 7.7 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.7 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 7.6 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 7.5 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 7.5 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 7.5 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 7.4 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.4 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 7.3 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 7.3 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 7.2 Ki ChEMBL
Q9HBY8 SGK2 Homo sapiens Human PF00069 PF00433 7.2 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 7.2 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.1 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 7.0 Ki ChEMBL
P29597 TYK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 7.0 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 7.0 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.9 Ki ChEMBL
P53667 LIMK1 Homo sapiens Human PF00412 PF00595 PF07714 6.8 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q13237 PRKG2 Homo sapiens Human PF00027 PF00069 6.7 Ki ChEMBL
Q9BXA7 TSSK1B Homo sapiens Human PF00069 6.7 Ki ChEMBL
O15530 PDPK1 Homo sapiens Human PF14593 PF00069 6.6 Ki ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.6 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.6 Ki ChEMBL
Q5VT25 CDC42BPA Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433 6.6 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.5 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.5 Ki ChEMBL
Q7KZI7 MARK2 Homo sapiens Human PF02149 PF00069 PF00627 6.5 Ki ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q9Y243 AKT3 Homo sapiens Human PF00169 PF00069 PF00433 6.5 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.4 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.3 Ki ChEMBL
P27448 MARK3 Homo sapiens Human PF02149 PF00069 PF00627 6.2 Ki ChEMBL
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 6.2 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.2 Ki ChEMBL
P05129 PRKCG Homo sapiens Human PF00130 PF00168 PF00069 PF00433 6.1 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
Q13554 CAMK2B Homo sapiens Human PF08332 PF00069 6.1 Ki ChEMBL
Q8TDC3 BRSK1 Homo sapiens Human PF21122 PF00069 PF21115 6.1 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.0 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.0 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.0 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL
Q9NR20 DYRK4 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL