5-(4-((1-(difluoromethyl)-1H-pyrazol-4-yl)amino)-1,3,5-triazin-2-yl)-2-(((3R,4S)-3-fluoro-1-(3-hydroxypropanoyl)piperidin-4-yl)oxy)benzonitrile

InChIKey	`ANVBJUPKQASFMW-AEFFLSMTSA-N`
Compound Name	5-(4-((1-(difluoromethyl)-1H-pyrazol-4-yl)amino)-1,3,5-triazin-2-yl)-2-(((3R,4S)-3-fluoro-1-(3-hydroxypropanoyl)piperidin-4-yl)oxy)benzonitrile
Canonical SMILES	`N#Cc1cc(-c2ncnc(Nc3cnn(C(F)F)c3)n2)ccc1O[C@H]1CCN(C(=O)CCO)C[C@H]1F`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.75
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q9UHD2	TBK1	Homo sapiens	Human	PF00069 PF18394 PF18396	7.2	IC50	ChEMBL;BindingDB
Q14164	IKBKE	Homo sapiens	Human	PF00069 PF18394 PF18396	7.0	IC50	BindingDB
O60674	JAK2	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	6.0	IC50	ChEMBL;BindingDB