3-amino-N-[4-[(dimethylamino)methyl]-3-pyridinyl]-6-(4-pyrrolidin-1-ylsulfonylphenyl)pyrazine-2-carboxamide

InChIKey	`AMZVBIHYDIQGRK-UHFFFAOYSA-N`
Compound Name	3-amino-N-[4-[(dimethylamino)methyl]-3-pyridinyl]-6-(4-pyrrolidin-1-ylsulfonylphenyl)pyrazine-2-carboxamide
Canonical SMILES	`CN(C)Cc1ccncc1NC(=O)c1nc(-c2ccc(S(=O)(=O)N3CCCC3)cc2)cnc1N`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	7.77
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P49841	GSK3B	Homo sapiens	Human	PF00069	9.3	Ki	ChEMBL;BindingDB
O96020	CCNE2	Homo sapiens	Human	PF02984 PF00134	7.2	Ki	ChEMBL
P24864	CCNE1	Homo sapiens	Human	PF02984 PF00134	7.2	Ki	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	7.2	Ki	ChEMBL