Molecule Details
| InChIKey | AMLGBGSXVKQKOZ-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-(5-(2-Amino-5-(4-(piperazin-1-yl)phenyl)pyridin-3-yl)-3-fluoro-2-methoxyphenyl)propane-1-sulfonamide |
| Canonical SMILES | CCCS(=O)(=O)Nc1cc(-c2cc(-c3ccc(N4CCNCC4)cc3)cnc2N)cc(F)c1OC |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.28 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O43353 | RIPK2 | Homo sapiens | Human | PF00619 PF07714 | 7.8 | IC50 | ChEMBL;BindingDB |
| Q9HC29 | NOD2 | Homo sapiens | Human | PF00619 PF13516 PF05729 PF17776 PF17779 | 7.6 | IC50 | ChEMBL;BindingDB |
| Q04771 | ACVR1 | Homo sapiens | Human | PF01064 PF07714 PF08515 | 6.5 | IC50 | ChEMBL;BindingDB |