Molecule Details
| InChIKey | AMHWQBGAKJESFB-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-(6,7-Dimethoxyquinazolin-4-yloxy)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methylbenzamide |
| Canonical SMILES | CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ncnc5cc(OC)c(OC)cc45)c3)cc2C(F)(F)F)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.29 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q12851 | MAP4K2 | Homo sapiens | Human | PF00780 PF00069 | 7.5 | IC50 | ChEMBL |
| P16591 | FER | Homo sapiens | Human | PF00611 PF07714 PF00017 | 7.4 | IC50 | ChEMBL |
| P07332 | FES | Homo sapiens | Human | PF00611 PF07714 PF00017 | 7.3 | IC50 | ChEMBL |
| O43318 | MAP3K7 | Homo sapiens | Human | PF07714 | 6.9 | IC50 | ChEMBL |