Molecule Details
| InChIKey | ALCVRKZFLFWUAZ-LSSUCPAZSA-N |
|---|---|
| Compound Name | (2E,4R,5E)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,5-dienamide |
| Canonical SMILES | C/C(=C\[C@H](C)/C=C/C(=O)NO)C(=O)c1ccc(N(C)C)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.72 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9UBN7 | HDAC6 | Homo sapiens | Human | PF00850 PF02148 | 8.3 | IC50 | BindingDB |
| Q13547 | HDAC1 | Homo sapiens | Human | PF00850 | 8.2 | IC50 | BindingDB |
| O15379 | HDAC3 | Homo sapiens | Human | PF00850 | 8.1 | IC50 | BindingDB |
| Q92769 | HDAC2 | Homo sapiens | Human | PF00850 | 7.8 | IC50 | BindingDB |
| Q969S8 | HDAC10 | Homo sapiens | Human | PF00850 | 7.5 | IC50 | BindingDB |
| Q9BY41 | HDAC8 | Homo sapiens | Human | PF00850 | 6.4 | IC50 | BindingDB |