Molecule Details
| InChIKey | AKXPLUFJRRUGNE-UHFFFAOYSA-N |
|---|---|
| Compound Name | 5-chloro-2-methyl-2-[3-(4-pyridin-2-ylpiperazin-1-yl)propyl]-3H-inden-1-one |
| Canonical SMILES | CC1(CCCN2CCN(c3ccccn3)CC2)Cc2cc(Cl)ccc2C1=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.81 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P08908 | HTR1A | Homo sapiens | Human | PF00001 | 9.1 | Ki | ChEMBL;BindingDB |
| P34969 | HTR7 | Homo sapiens | Human | PF00001 | 8.1 | Ki | ChEMBL;BindingDB |
| P21917 | DRD4 | Homo sapiens | Human | PF00001 | 7.3 | Ki | ChEMBL;BindingDB |
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 6.7 | Ki | ChEMBL;BindingDB |