N-(3-(oxazol-4-yl)phenyl)-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine

InChIKey	`AKEMXASAMBDUOC-UHFFFAOYSA-N`
Compound Name	N-(3-(oxazol-4-yl)phenyl)-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine
Canonical SMILES	`c1cc(Nc2nccc(-c3cnn4ncccc34)n2)cc(-c2cocn2)c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	8.38
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P11802	CDK4	Homo sapiens	Human	PF00069	8.5	pIC50	TTD_MultiTarget
P24941	CDK2	Homo sapiens	Human	PF00069	8.5	pIC50	TTD_MultiTarget
P49841	GSK3B	Homo sapiens	Human	PF00069	8.1	IC50	ChEMBL;BindingDB