Molecule Details
InChIKeyAJTBUWMKUOLMNM-UHFFFAOYSA-N
Compound Name3,10-dihydroxy-7H-chromeno[3,4-b]indol-6-one
Canonical SMILESO=c1oc2cc(O)ccc2c2c1[nH]c1ccc(O)cc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL6.75
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
P11387 TOP1 Homo sapiens Human PF14370 PF01028 PF02919 7.4 IC50 ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.2 IC50 ChEMBL;BindingDB
P49840 GSK3A Homo sapiens Human PF00069 6.5 IC50 ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.5 IC50 ChEMBL;BindingDB
Q00535 CDK5 Homo sapiens Human PF00069 6.1 IC50 ChEMBL;BindingDB