8-Amino-2-cyclohexyl-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3,4-dihydro-2,7-naphthyridin-1-one

InChIKey	`AJRCHNXNYNADRQ-UHFFFAOYSA-N`
Compound Name	8-Amino-2-cyclohexyl-5-[1-(1-methylpiperidin-4-yl)pyrazol-4-yl]-3,4-dihydro-2,7-naphthyridin-1-one
Canonical SMILES	`CN1CCC(n2cc(-c3cnc(N)c4c3CCN(C3CCCCC3)C4=O)cn2)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.42
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P37023	ACVRL1	Homo sapiens	Human	PF07714 PF08515	7.8	IC50	ChEMBL
Q04771	ACVR1	Homo sapiens	Human	PF01064 PF07714 PF08515	7.7	IC50	ChEMBL
P36894	BMPR1A	Homo sapiens	Human	PF01064 PF07714 PF08515	6.8	IC50	ChEMBL