tert-butyl 3-(3-(((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)carbamoyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methylthiophen-2-yl)pyrrolidine-1-carboxylate

InChIKey	`AHMAQXSPEKRSCD-UHFFFAOYSA-N`
Compound Name	tert-butyl 3-(3-(((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)carbamoyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methylthiophen-2-yl)pyrrolidine-1-carboxylate
Canonical SMILES	`CCN(c1sc(C2CCN(C(=O)OC(C)(C)C)C2)c(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	6.46
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q15910	EZH2	Homo sapiens	Human	PF21358 PF11616 PF18118 PF18264 PF00856	6.7	IC50	ChEMBL;BindingDB
O75530	EED	Homo sapiens	Human	PF00400	6.4	IC50	ChEMBL
Q09028	RBBP4	Homo sapiens	Human	PF12265 PF00400	6.4	IC50	ChEMBL
Q15022	SUZ12	Homo sapiens	Human	PF09733 PF23320	6.4	IC50	ChEMBL
Q6ZN18	AEBP2	Homo sapiens	Human	PF26014	6.4	IC50	ChEMBL