Molecule Details
InChIKeyAFQAFERZBGFZRQ-UHFFFAOYSA-N
Compound Name3-(2-Fluoroethyl)spiro[8-oxa-3,11-diazatricyclo[7.4.0.02,6]trideca-1(9),2(6),4,10,12-pentaene-7,1'-cyclobutane]-4-carboxamide
Canonical SMILESNC(=O)c1cc2c(n1CCF)-c1ccncc1OC21CCC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)4
Pfam Stratification Cross-Family
Avg pChEMBL8.9
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
P49336 CDK8 Homo sapiens Human PF00069 9.6 IC50 ChEMBL;BindingDB
P24863 CCNC Homo sapiens Human PF16899 PF00134 9.3 IC50 ChEMBL
Q9BWU1 CDK19 Homo sapiens Human PF00069 9.1 IC50 ChEMBL;BindingDB
Q8TF76 HASPIN Homo sapiens Human PF12330 7.6 IC50 ChEMBL;BindingDB