Molecule Details
| InChIKey | AFCYMBUDPUSDIK-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[[4-(3-hydroxyprop-1-ynyl)-3-methyl-7-[4-(trifluoromethoxy)phenyl]benzimidazol-5-yl]methyl]prop-2-enamide |
| Canonical SMILES | C=CC(=O)NCc1cc(-c2ccc(OC(F)(F)F)cc2)c2ncn(C)c2c1C#CCO |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.0 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15561 | TEAD4 | Homo sapiens | Human | PF01285 PF17725 | 8.5 | IC50 | ChEMBL |
| P28347 | TEAD1 | Homo sapiens | Human | PF01285 PF17725 | 8.2 | IC50 | ChEMBL |
| Q15562 | TEAD2 | Homo sapiens | Human | PF01285 PF17725 | 8.2 | IC50 | ChEMBL |
| Q99594 | TEAD3 | Homo sapiens | Human | PF01285 PF17725 | 7.0 | IC50 | ChEMBL |