Molecule Details
InChIKeyAEZZJXJIJFSUEM-QFIPXVFZSA-N
Canonical SMILESCc1ccc(-n2nccn2)c(C(=O)N2CCCO[C@H]2Cn2ccc(-c3ccc(F)cn3)n2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.94
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB21483
Drug NameVornorexant
CAS Number2265899-49-6
Groups experimental
ATC Codes nan
DescriptionVornorexant is a small molecule drug. The usage of the INN stem '-orexant' in the name indicates that Vornorexant is a orexin receptor antagonist. Vornorexant has a monoisotopic molecular weight of 447.18 Da.

Cross-references: BindingDB: 50543827 CHEMBL4638046
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
O43613 HCRTR1 Homo sapiens Human PF00001 9.0 IC50 ChEMBL;BindingDB
O43614 HCRTR2 Homo sapiens Human PF00001 PF03827 8.9 IC50 ChEMBL;BindingDB