Molecule Details
InChIKeyAEYLJTAIDDIOBA-UHFFFAOYSA-N
Compound NameN-[3-hydroxy-4-(piperazine-1-carbonyl)phenyl]propanamide
Canonical SMILESCCC(=O)Nc1ccc(C(=O)N2CCNCC2)c(O)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)53
Pfam Stratification Cross-Family
Avg pChEMBL6.52
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (53)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.4 Ki ChEMBL
P08581 MET Homo sapiens Human PF07714 PF01437 PF01403 PF01833 7.3 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 7.3 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 7.2 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 7.1 Ki ChEMBL
P29376 LTK Homo sapiens Human PF12810 PF07714 7.1 Ki ChEMBL
P34947 GRK5 Homo sapiens Human PF00069 PF00615 7.1 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 7.0 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.0 Ki ChEMBL
Q06418 TYRO3 Homo sapiens Human PF00041 PF07679 PF07714 7.0 Ki ChEMBL
P04629 NTRK1 Homo sapiens Human PF13855 PF16920 PF07714 PF18613 6.9 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.9 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.9 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.9 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.8 Ki ChEMBL
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 6.8 Ki ChEMBL
Q9UQM7 CAMK2A Homo sapiens Human PF08332 PF00069 6.8 Ki ChEMBL
P36507 MAP2K2 Homo sapiens Human PF00069 6.7 Ki ChEMBL
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 6.6 Ki ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P09619 PDGFRB Homo sapiens Human PF00047 PF13927 PF25305 PF07714 6.5 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.5 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q8IU85 CAMK1D Homo sapiens Human PF00069 6.5 Ki ChEMBL
O14757 CHEK1 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P08069 IGF1R Homo sapiens Human PF00757 PF07714 PF01030 6.4 Ki ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q02750 MAP2K1 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.4 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 6.4 Ki ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.3 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.3 Ki ChEMBL
P51955 NEK2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P53667 LIMK1 Homo sapiens Human PF00412 PF00595 PF07714 6.3 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.3 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.2 Ki ChEMBL
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.2 Ki ChEMBL
Q04912 MST1R Homo sapiens Human PF07714 PF01437 PF01403 PF01833 6.2 Ki ChEMBL
Q07912 TNK2 Homo sapiens Human PF09027 PF11555 PF07714 PF22931 PF14604 6.2 Ki ChEMBL
Q9UM73 ALK Homo sapiens Human PF12810 PF00629 PF07714 6.2 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.1 Ki ChEMBL
O96013 PAK4 Homo sapiens Human PF00786 PF00069 6.1 Ki ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.1 Ki ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q04759 PRKCQ Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.1 Ki ChEMBL
Q16620 NTRK2 Homo sapiens Human PF07679 PF13855 PF16920 PF01462 PF07714 6.1 Ki ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.0 Ki ChEMBL
P16234 PDGFRA Homo sapiens Human PF07679 PF25305 PF07714 6.0 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.0 Ki ChEMBL
Q16539 MAPK14 Homo sapiens Human PF00069 6.0 Ki ChEMBL