Molecule Details
InChIKeyAECDBHGVIIRMOI-GRGXKFILSA-N
Canonical SMILESNc1ncnc2c1c(-c1cccc(OCc3ccccc3)c1)cn2[C@H]1C[C@@H](CN2CCC2)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL6.44
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P08069 IGF1R Homo sapiens Human PF00757 PF07714 PF01030 7.2 IC50 ChEMBL;BindingDB
Q12809 KCNH2 Homo sapiens Human PF00027 PF00520 PF13426 6.9 IC50 ChEMBL;BindingDB
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.4 IC50 ChEMBL
Q02763 TEK Homo sapiens Human PF00041 PF10430 PF07714 6.3 IC50 ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.2 IC50 ChEMBL
P16234 PDGFRA Homo sapiens Human PF07679 PF25305 PF07714 6.1 IC50 ChEMBL;BindingDB
P06213 INSR Homo sapiens Human PF00757 PF17870 PF07714 PF01030 6.0 IC50 ChEMBL;BindingDB