Molecule Details
| InChIKey | ADXGNEYLLLSOAR-UHFFFAOYSA-N |
|---|---|
| Compound Name | Tasosartan |
| Canonical SMILES | Cc1nc(C)c2c(n1)N(Cc1ccc(-c3ccccc3-c3nnn[nH]3)cc1)C(=O)CC2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.95 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB01349 |
|---|---|
| Drug Name | Tasosartan |
| CAS Number | 145733-36-4 |
| Groups | experimental |
| ATC Codes | C09CA05 |
| Description | Tasosartan is a long-acting angiotensin II (AngII) receptor blocker. Its long duration of action has been attributed to its active metabolite enoltasosartan. It is used to treat patients with essential hypertension. |
Categories: Agents Acting on the Renin-Angiotensin System Agents causing hyperkalemia Angiotensin II receptor blockers (ARBs), plain Angiotensin Receptor Antagonists Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Substrates
Cross-references: BindingDB: 50040439 ChEBI: 135666 CHEMBL432162 ChemSpider: 54890 PharmGKB: PA164769057 PubChem:60919 PubChem:46504809 Therapeutic Targets Database: DAP001258 Wikipedia: Tasosartan ZINC: ZINC000013444037