Molecule Details
InChIKeyADQZGIYHFQQPRB-UHFFFAOYSA-N
Compound NameRwj-68354
Canonical SMILESCOc1cc(N)[nH]c2nc(-c3ccc(F)cc3)c(-c3ccncc3)c1-2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL7.0
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
O15264 MAPK13 Homo sapiens Human PF00069 8.2 IC50 ChEMBL
P53778 MAPK12 Homo sapiens Human PF00069 8.2 IC50 ChEMBL
Q15759 MAPK11 Homo sapiens Human PF00069 8.2 IC50 ChEMBL
Q16539 MAPK14 Homo sapiens Human PF00069 8.2 IC50 ChEMBL;BindingDB
P10635 CYP2D6 Homo sapiens Human PF00067 6.7 IC50 ChEMBL
P29274 ADORA2A Homo sapiens Human PF00001 6.2 Ki ChEMBL
P28335 HTR2C Homo sapiens Human PF00001 6.2 Ki ChEMBL
P30542 ADORA1 Homo sapiens Human PF00001 6.2 IC50 ChEMBL
P08684 CYP3A4 Homo sapiens Human PF00067 6.0 IC50 ChEMBL
P11712 CYP2C9 Homo sapiens Human PF00067 6.0 IC50 ChEMBL