Molecule Details
InChIKeyADPGBLDMLCUZBX-RTWAWAEBSA-N
Compound Name2-(1H-indol-5-yl)-5-[[(2R,3S)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl]oxy]-1,3,4-thiadiazole
Canonical SMILESc1cncc(C[C@@H]2[C@@H](Oc3nnc(-c4ccc5[nH]ccc5c4)s3)C3CCN2CC3)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Homologous
Avg pChEMBL6.8
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
P36544 CHRNA7 Homo sapiens Human PF02931 PF02932 8.0 Ki ChEMBL
P17787 CHRNB2 Homo sapiens Human PF02931 PF02932 6.7 Ki ChEMBL
P43681 CHRNA4 Homo sapiens Human PF02931 PF02932 6.7 Ki ChEMBL
P30926 CHRNB4 Homo sapiens Human PF02931 PF02932 6.4 Ki ChEMBL
P32297 CHRNA3 Homo sapiens Human PF02931 PF02932 6.4 Ki ChEMBL