Molecule Details
| InChIKey | ACWKGTGIJRCOOM-UHFFFAOYSA-N |
|---|---|
| Compound Name | Atuveciclib Racemate |
| Canonical SMILES | COc1cc(F)ccc1-c1ncnc(Nc2cccc(CS(C)(=N)=O)c2)n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.01 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O60563 | CCNT1 | Homo sapiens | Human | PF00134 PF21797 | 7.9 | IC50 | BindingDB |
| P49840 | GSK3A | Homo sapiens | Human | PF00069 | 7.3 | IC50 | BindingDB |
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 7.1 | IC50 | BindingDB |
| P50750 | CDK9 | Homo sapiens | Human | PF00069 | 6.4 | IC50 | BindingDB |
| P24941 | CDK2 | Homo sapiens | Human | PF00069 | 6.3 | IC50 | BindingDB |