Molecule Details
| InChIKey | ACSDLURGGYXLSE-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-[4-[(4-Fluorophenyl)methyl]piperazin-1-yl]-7-methoxypyrrolo[1,2-a]quinoxaline |
| Canonical SMILES | COc1ccc2c(c1)nc(N1CCN(Cc3ccc(F)cc3)CC1)c1cccn12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.18 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| A5X5Y0 | HTR3E | Homo sapiens | Human | PF02931 PF02932 | 8.2 | IC50 | ChEMBL |
| O95264 | HTR3B | Homo sapiens | Human | PF02931 PF02932 | 8.2 | IC50 | ChEMBL |
| P46098 | HTR3A | Homo sapiens | Human | PF02931 PF02932 | 8.2 | IC50 | ChEMBL;BindingDB |
| Q70Z44 | HTR3D | Homo sapiens | Human | PF02931 PF02932 | 8.2 | IC50 | ChEMBL |
| Q8WXA8 | HTR3C | Homo sapiens | Human | PF02931 PF02932 | 8.2 | IC50 | ChEMBL |