Molecule Details
| InChIKey | ACPHUHSYZGYUCK-NDDJGDGRSA-N |
|---|---|
| Compound Name | (3R)-1,1-dimethyl-3-[4-[(E)-2-phenylethenyl]phenoxy]pyrrolidin-1-ium |
| Canonical SMILES | C[N+]1(C)CC[C@@H](Oc2ccc(/C=C/c3ccccc3)cc2)C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.72 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P17787 | CHRNB2 | Homo sapiens | Human | PF02931 PF02932 | 8.0 | Ki | ChEMBL |
| P43681 | CHRNA4 | Homo sapiens | Human | PF02931 PF02932 | 8.0 | Ki | ChEMBL |
| P36544 | CHRNA7 | Homo sapiens | Human | PF02931 PF02932 | 7.6 | Ki | ChEMBL |
| Q9GZZ6 | CHRNA10 | Homo sapiens | Human | PF02931 PF02932 | 7.4 | IC50 | ChEMBL |
| Q9UGM1 | CHRNA9 | Homo sapiens | Human | PF02931 PF02932 | 7.4 | IC50 | ChEMBL |