Molecule Details
InChIKeyACLLLJSNOCYQOJ-UHFFFAOYSA-N
Compound NameGrk6-IN-1
Canonical SMILESCCc1cc(Nc2nc(NCc3ccc(Cl)cc3OC)nc3cccc(OC)c23)n[nH]1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL7.26
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q8WTQ7 GRK7 Homo sapiens Human PF00069 PF00615 8.2 IC50 ChEMBL;BindingDB
P43250 GRK6 Homo sapiens Human PF00069 PF00615 8.1 IC50 ChEMBL;BindingDB
P34947 GRK5 Homo sapiens Human PF00069 PF00615 7.9 IC50 ChEMBL;BindingDB
P32298 GRK4 Homo sapiens Human PF00069 PF00615 7.7 IC50 ChEMBL;BindingDB
Q15835 GRK1 Homo sapiens Human PF00069 PF00615 7.3 IC50 ChEMBL;BindingDB
Q05397 PTK2 Homo sapiens Human PF21477 PF00373 PF18038 PF03623 PF07714 6.7 IC50 ChEMBL;BindingDB
O43293 DAPK3 Homo sapiens Human PF00069 6.1 IC50 ChEMBL;BindingDB
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.1 IC50 ChEMBL;BindingDB