Molecule Details
| InChIKey | ABJKWBDEJIDSJZ-UHFFFAOYSA-N |
|---|---|
| Canonical SMILES | CN(Cc1ccc(C(C)(C)C)cc1)Cc1cccc2ccccc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.32 |
| Source | ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB01091 |
|---|---|
| Drug Name | Butenafine |
| CAS Number | 101828-21-1 |
| Groups | approved |
| ATC Codes | D01AE23 |
| Description | Butenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols. In particular, butenafine acts to inhibit the activity of the squalene epoxidase enzyme that is essential in the formation of sterols nec... |
Categories: Amines Anti-Infective Agents Antifungal Agents Antifungals for Dermatological Use Antifungals for Topical Use Benzene Derivatives Benzyl Compounds Benzylamine Antifungal Benzylamines Dermatologicals
Cross-references: BindingDB: 50436713 ChEBI: 3238 CHEMBL990 ChemSpider: 2390 Drugs Product Database (DPD): 11423 C08067 D07596 PharmGKB: PA164745478 PubChem:2484 PubChem:46506191 RxCUI: 47461 Therapeutic Targets Database: DAP001236 Wikipedia: Butenafine ZINC: ZINC000001530975