Molecule Details
InChIKeyAAYZTFLAQXDFOL-UHFFFAOYSA-N
Compound Name1-[4-(4-Aminothieno[3,2-c]pyridin-3-yl)phenyl]-3-[2-(trifluoromethyl)phenyl]urea
Canonical SMILESNc1nccc2scc(-c3ccc(NC(=O)Nc4ccccc4C(F)(F)F)cc3)c12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL6.63
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
Q96GD4 AURKB Homo sapiens Human PF00069 8.2 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 7.9 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.8 Ki ChEMBL
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 6.7 Ki ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.6 Ki ChEMBL
P08922 ROS1 Homo sapiens Human PF00041 PF07714 6.5 Ki ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.1 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.1 Ki ChEMBL
P30530 AXL Homo sapiens Human PF00041 PF13927 PF07714 6.0 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.0 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL