Molecule Details
InChIKeyAAKGHBVKMSAASI-UHFFFAOYSA-N
Canonical SMILESCOc1ncc(-c2cc(NC(=O)c3cc(C(F)(F)F)ccn3)ccc2C)cc1C1(F)COC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.28
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P04049 RAF1 Homo sapiens Human PF00130 PF07714 PF02196 6.5 IC50 ChEMBL;BindingDB
P15056 BRAF Homo sapiens Human PF00130 PF07714 PF02196 6.0 IC50 ChEMBL;BindingDB