Cortisol synthesis and secretion
hsa04927 42 targets in this pathway
| UniProt AC | Gene | Protein Name | Organism | Multi-Target Molecules | |
|---|---|---|---|---|---|
P15538 |
CYP11B1 | Cytochrome P450 11B1, mitochondrial | Homo sapiens | 790 | Detail |
P30556 |
AGTR1 | Type-1 angiotensin II receptor | Homo sapiens | 696 | Detail |
P17612 |
PRKACA | cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens | 453 | Detail |
O95180 |
CACNA1H | Voltage-dependent T-type calcium channel subunit alpha-1H | Homo sapiens | 265 | Detail |
O43497 |
CACNA1G | Voltage-dependent T-type calcium channel subunit alpha-1G | Homo sapiens | 265 | Detail |
P01130 |
LDLR | Low-density lipoprotein receptor | Homo sapiens | 224 | Detail |
Q9P0X4 |
CACNA1I | Voltage-dependent T-type calcium channel subunit alpha-1I | Homo sapiens | 214 | Detail |
O14649 |
KCNK3 | Potassium channel subfamily K member 3 | Homo sapiens | 148 | Detail |
Q13936 |
CACNA1C | Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens | 147 | Detail |
P05093 |
CYP17A1 | Steroid 17-alpha-hydroxylase/17,20 lyase | Homo sapiens | 125 | Detail |
P22694 |
PRKACB | cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens | 121 | Detail |
Q01668 |
CACNA1D | Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens | 117 | Detail |
O60840 |
CACNA1F | Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens | 117 | Detail |
Q13698 |
CACNA1S | Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens | 117 | Detail |
P22612 |
PRKACG | cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens | 111 | Detail |
Q96D31 |
ORAI1 | Calcium release-activated calcium channel protein 1 | Homo sapiens | 97 | Detail |
O95069 |
KCNK2 | Potassium channel subfamily K member 2 | Homo sapiens | 48 | Detail |
Q13285 |
NR5A1 | Steroidogenic factor 1 | Homo sapiens | 32 | Detail |
Q08828 |
ADCY1 | Adenylate cyclase type 1 | Homo sapiens | 30 | Detail |
P40145 |
ADCY8 | Adenylate cyclase type 8 | Homo sapiens | 27 | Detail |
O60658 |
PDE8A | High affinity cAMP-specific and IBMX-insensitive 3',5'-cycli | Homo sapiens | 25 | Detail |
O95622 |
ADCY5 | Adenylate cyclase type 5 | Homo sapiens | 23 | Detail |
Q08462 |
ADCY2 | Adenylate cyclase type 2 | Homo sapiens | 21 | Detail |
O60266 |
ADCY3 | Adenylate cyclase type 3 | Homo sapiens | 21 | Detail |
O43306 |
ADCY6 | Adenylate cyclase type 6 | Homo sapiens | 21 | Detail |
P51828 |
ADCY7 | Adenylate cyclase type 7 | Homo sapiens | 21 | Detail |
O60503 |
ADCY9 | Adenylate cyclase type 9 | Homo sapiens | 21 | Detail |
Q8NFM4 |
ADCY4 | Adenylate cyclase type 4 | Homo sapiens | 21 | Detail |
P14060 |
HSD3B1 | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase ty | Homo sapiens | 19 | Detail |
O95263 |
PDE8B | High affinity cAMP-specific and IBMX-insensitive 3',5'-cycli | Homo sapiens | 16 | Detail |
P08686 |
CYP21A2 | Steroid 21-hydroxylase | Homo sapiens | 15 | Detail |
P22736 |
NR4A1 | Nuclear receptor subfamily 4immunitygroup A member 1 | Homo sapiens | 4 | Detail |
Q14643 |
ITPR1 | Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 | Homo sapiens | 4 | Detail |
Q14573 |
ITPR3 | Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 | Homo sapiens | 4 | Detail |
Q14571 |
ITPR2 | Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2 | Homo sapiens | 3 | Detail |
P29992 |
GNA11 | Guanine nucleotide-binding protein subunit alpha-11 | Homo sapiens | 2 | Detail |
P50148 |
GNAQ | Guanine nucleotide-binding protein G(q) subunit alpha | Homo sapiens | 2 | Detail |
P22459 |
KCNA4 | Potassium voltage-gated channel subfamily A member 4 | Homo sapiens | 2 | Detail |
P51843 |
NR0B1 | Nuclear receptor subfamily 0 group B member 1 | Homo sapiens | 1 | Detail |
Q01718 |
MC2R | Adrenocorticotropic hormone receptor | Homo sapiens | 1 | Detail |
Q8WTV0 |
SCARB1 | Scavenger receptor class B member 1 | Homo sapiens | 1 | Detail |
P01019 |
AGT | Angiotensinogen | Homo sapiens | 0 | Detail |