Longevity regulating pathway - multiple species

hsa04213 46 targets in this pathway

UniProt AC Gene Protein Name Organism Multi-Target Molecules
Q13547 HDAC1 Histone deacetylase 1 Homo sapiens 5940 Detail
P42336 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic sub Homo sapiens 5616 Detail
Q92769 HDAC2 Histone deacetylase 2 Homo sapiens 3821 Detail
O00329 PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic sub Homo sapiens 3772 Detail
P27986 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha Homo sapiens 2553 Detail
P42345 MTOR Serine/threonine-protein kinase mTOR Homo sapiens 2517 Detail
P42338 PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic sub Homo sapiens 1951 Detail
P01116 KRAS GTPase KRas Homo sapiens 1811 Detail
P31749 AKT1 RAC-alpha serine/threonine-protein kinase Homo sapiens 1633 Detail
P23443 RPS6KB1 Ribosomal protein S6 kinase beta-1 Homo sapiens 1180 Detail
P01111 NRAS GTPase NRas Homo sapiens 923 Detail
P31751 AKT2 RAC-beta serine/threonine-protein kinase Homo sapiens 896 Detail
P06213 INSR Insulin receptor Homo sapiens 656 Detail
P08069 IGF1R Insulin-like growth factor 1 receptor Homo sapiens 611 Detail
O00459 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta Homo sapiens 485 Detail
P17612 PRKACA cAMP-dependent protein kinase catalytic subunit alpha Homo sapiens 453 Detail
Q9Y243 AKT3 RAC-gamma serine/threonine-protein kinase Homo sapiens 321 Detail
Q92569 PIK3R3 Phosphatidylinositol 3-kinase regulatory subunit gamma Homo sapiens 289 Detail
Q13131 PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 Homo sapiens 282 Detail
Q8N122 RPTOR Regulatory-associated protein of mTOR Homo sapiens 189 Detail
P22694 PRKACB cAMP-dependent protein kinase catalytic subunit beta Homo sapiens 121 Detail
P22612 PRKACG cAMP-dependent protein kinase catalytic subunit gamma Homo sapiens 111 Detail
P54619 PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 Homo sapiens 83 Detail
Q96EB6 SIRT1 NAD-dependent protein deacetylase sirtuin-1 Homo sapiens 78 Detail
P54646 PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens 75 Detail
Q9Y478 PRKAB1 5'-AMP-activated protein kinase subunit beta-1 Homo sapiens 65 Detail
O43741 PRKAB2 5'-AMP-activated protein kinase subunit beta-2 Homo sapiens 45 Detail
Q9UGJ0 PRKAG2 5'-AMP-activated protein kinase subunit gamma-2 Homo sapiens 44 Detail
Q08828 ADCY1 Adenylate cyclase type 1 Homo sapiens 30 Detail
Q9UGI9 PRKAG3 5'-AMP-activated protein kinase subunit gamma-3 Homo sapiens 30 Detail
P40145 ADCY8 Adenylate cyclase type 8 Homo sapiens 27 Detail
O95622 ADCY5 Adenylate cyclase type 5 Homo sapiens 23 Detail
Q96B36 AKT1S1 Proline-rich AKT1 substrate 1 Homo sapiens 22 Detail
Q08462 ADCY2 Adenylate cyclase type 2 Homo sapiens 21 Detail
O60266 ADCY3 Adenylate cyclase type 3 Homo sapiens 21 Detail
O43306 ADCY6 Adenylate cyclase type 6 Homo sapiens 21 Detail
P51828 ADCY7 Adenylate cyclase type 7 Homo sapiens 21 Detail
O60503 ADCY9 Adenylate cyclase type 9 Homo sapiens 21 Detail
Q8NFM4 ADCY4 Adenylate cyclase type 4 Homo sapiens 21 Detail
P01112 HRAS GTPase HRas Homo sapiens 14 Detail
Q9UBS0 RPS6KB2 Ribosomal protein S6 kinase beta-2 Homo sapiens 13 Detail
P0DMV8 HSPA1A Heat shock 70 kDa protein 1A Homo sapiens 6 Detail
P11142 HSPA8 Heat shock cognate 71 kDa protein Homo sapiens 5 Detail
P35568 IRS1 Insulin receptor substrate 1 Homo sapiens 2 Detail
P0DMV9 HSPA1B Heat shock 70 kDa protein 1B Homo sapiens 1 Detail
P04040 CAT Catalase Homo sapiens 1 Detail